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Epetraborole hydrochloride
CAS No. 1234563-16-6
Epetraborole hydrochloride ( GSK2251052 hydrochloride;AN3365 )
产品货号. M10938 CAS No. 1234563-16-6
Epetraborole (GSK2251052, AN3365) is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥915 | 有现货 |
|
| 10MG | ￥1531 | 有现货 |
|
| 25MG | ￥3418 | 有现货 |
|
| 50MG | ￥5087 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Epetraborole hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Epetraborole (GSK2251052, AN3365) is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS).
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产品描述Epetraborole (GSK2251052, AN3365) is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS), shows MIC50/MIC90 of 2/4 ug/ml against 916 clinical anaerobic isolates; MIC90s against 302 Bacteroides fragilis and Bacteroides thetaiotaomicron strains are 4 and 8 μg/ml, respectively; a single amino acid polymorphism (P329) within the editing domain of LeuRS reduces susceptibility to GSK2251052.Bacterial Infection Phase 2 Discontinued
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同义词GSK2251052 hydrochloride;AN3365
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通路GPCR/G Protein
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靶点Antibacterial
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受体bacterialleucyltRNAsynthetase
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number1234563-16-6
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分子量273.52
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分子式C11H17BClNO4
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纯度>98% (HPLC)
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溶解度H2O: ≥ 28 mg/mL
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SMILESB1(C2=C(C=CC=C2OCCCO)C(O1)CN)O.Cl
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化学全称1-Propanol, 3-[[(3S)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl]oxy]-, hydrochloride (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Goldstein EJ, et al. Antimicrob Agents Chemother. 2013 May;57(5):2401-4.
2. Tenero D, et al. Antimicrob Agents Chemother. 2013 Jul;57(7):3334-9.
3. O'Dwyer K, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):289-98.
4. Gupta A, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3219-21.
2. Tenero D, et al. Antimicrob Agents Chemother. 2013 Jul;57(7):3334-9.
3. O'Dwyer K, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):289-98.
4. Gupta A, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3219-21.
产品手册
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